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. 2010 Aug 31;8(8):e1000472.
doi: 10.1371/journal.pbio.1000472.

Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets

Thomas Kelder  1 , Bruce R Conklin, Chris T Evelo, Alexander R Pico
Affiliations

Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets

Thomas Kelder et al. PLoS Biol. .

Abstract

This Essay discusses the role of pathways for exploratory data analysis in present-day biology.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Pathways for exploratory data analysis.
Biological pathways are powerful visualization tools for data exploration, focused on finding the right question.
See this image and copyright information in PMC

References

    1. Tukey J. W. Exploratory data analysis. Reading, MA: Addison-Wesley; 1977. 688
    1. Tukey J. W. We need both exploratory and confirmatory. Am Stat. 1980;34:4.
    1. Pathguide. Available: http://www.pathguide.org. Accessed 29 July 2010.
    1. BioPAX. Available: http://www.biopax.org. Accessed 29 July 2010.
    1. Saraiya P, North C, Duca K. Visualizing biological pathways: requirements analysis, systems evaluation and research agenda. Inf Vis. 2005;4:15.

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