Immune modulators as therapeutic agents for cutaneous T-cell lymphoma
- PMID: 20826407
- PMCID: PMC3877673
- DOI: 10.3816/CLML.2010.s.017
Immune modulators as therapeutic agents for cutaneous T-cell lymphoma
Abstract
Cutaneous T-cell lymphoma at all stages appears to be responsive to immune modulatory therapeutic approaches. We describe here the mechanistic rationale for the use of interferons, interleukin-12, retinoids, Toll-like receptor agonists, photopheresis and combinations of immune preserving, immune stimulatory therapies for CTCL.
Conflict of interest statement
There were no conflicts of interest in regard to this publication
References
-
- Walsh PT, Benoit BM, Wysocka M, Dalton NM, Turka LA, Rook AH. A role for regulatory T cells in cutaneous T-Cell lymphoma; induction of a CD4 + CD25 + Foxp3+ T-cell phenotype associated with HTLV-1 infection. J Invest Dermatol. 2006;126(3):690–2. - PubMed
-
- Olsen EA. Interferon in the treatment of cutaneous T-cell lymphoma. Dermatol Ther. 2003;16(4):311–21. - PubMed
-
- McGinnis KS, Ubriani R, Newton S, Junkins-Hopkins JM, Vittorio CC, Kim EJ, et al. The addition of interferon gamma to oral bexarotene therapy with photopheresis for Sezary syndrome. Arch Dermatol. 2005;141(9):1176–8. - PubMed
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