[Cyclic 3--5-adenosine monophosphate metabolism in patients with Duchenne myodystrophy]

Abstract

The state of metabolism of cyclic adenosinmonophosphate was studied. It was established that the concentration of nucleotides was distinctly lower in patients with this disease. The activity of adenilacyclose did not differ from normal rates. The enzyme to a large degree lost its capability of reacting to hormones, which made the metabolism in tissues to a certain extent autonomous. These data permit to rise the question of conducting a correcting treatment. In other forms of progressive muscular dystrophy the level of cyclic adenosinmonophosphate did not differ significantly from normal indices.