Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Sep;26(9):496-501.
doi: 10.1016/S1607-551X(10)70078-4.

Ganglioneuroma of posterior mediastinum in a 6-year-old girl: imaging for pediatric intrathoracic incidentaloma

Affiliations
Case Reports

Ganglioneuroma of posterior mediastinum in a 6-year-old girl: imaging for pediatric intrathoracic incidentaloma

Pei-Chin Lin et al. Kaohsiung J Med Sci. 2010 Sep.

Abstract

Intrathoracic tumor is a rare entity in the pediatric population and neurogenic tumors account for 40-50% of childhood intrathoracic tumors. They can cause severe symptoms, such as respiratory distress, neurological dysfunction and metabolic disturbances. Posterior mediastinal ganglioneuroma (GN) usually occurs in children and can be found accidentally. Precise preoperative diagnosis is very difficult and has a great influence on surgical intervention. Here, we report a 6-year-old girl with a posterior mediastinal GN that was found incidentally on chest radiography. Computed tomography and magnetic resonance imaging demonstrated a right paraspinal tumor with punctuate calcification and intraspinal extension. (18)F-fluorodeoxyglucose positron emission tomography revealed low-grade fluorodeoxyglucose avidity of this tumor. Computed tomography and magnetic resonance imaging can characterize GN and positron emission tomography is helpful for differentiating benign or malignant lesions.

PubMed Disclaimer

References

    1. Joshi VV, Cantor AB, Altshuler G, et al. Recommendations for modification of terminology of neuro‐blastic tumors and prognostic significance of Shimada classification. A clinicopathologic study of 213 cases from the Pediatric Oncology Group. Cancer. 1992; 69: 2183–2196. - PubMed
    1. Shimada H, Chatten J, Newton WA, et al. Histopatho‐logic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age‐linked classification of neuroblastomas. J Natl Cancer Inst. 1984; 73: 405–416. - PubMed
    1. Weiss S, Sobin L. Histological Typing of Soft Tissue Tumors, 2nd edition. International Histological Classification of Tumors. Berlin: Springer. 1994.
    1. Christein JD, Kim AW, Jakate S, et al. Central pancreatectomy for a pancreatic ganglioneuroma in a patient with previous neuroblastoma. Pancreatology. 2002; 2: 557–560. - PubMed
    1. Schulman H, Laufer L, Barki Y, et al. Ganglioneuroma: an ‘incidentaloma’ of childhood. Eur Radiol. 1998; 8: 582–584. - PubMed

Publication types

LinkOut - more resources