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. 2010 Oct;35(10):776-9.
doi: 10.1097/RLU.0b013e3181e4da32.

The utility of F-18 FDG PET/CT in the evaluation of pancreatic intraductal papillary mucinous neoplasm

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The utility of F-18 FDG PET/CT in the evaluation of pancreatic intraductal papillary mucinous neoplasm

Hye-Suk Hong et al. Clin Nucl Med. 2010 Oct.

Abstract

Purpose: To assess the utility of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in evaluating pancreatic intraductal papillary mucinous neoplasm (IPMN).

Materials and methods: We included 31 patients with pancreatic IPMN who underwent F-18 FDG PET/CT and multidetector CT (MDCT). Each pancreatic lesion was classified as benign or malignant. On PET, the maximal standardized uptake value was measured in each pancreatic lesion.

Results: PET/CT was superior to MDCT in diagnosing malignant IPMN. All 22 concordant results gave accurate diagnoses. Of 9 discordant results, MDCT misdiagnosed 7 IPMNs, whereas PET/CT misinterpreted 2. Malignant IPMNs showed significantly higher maximal standardized uptake values (mean ± standard deviation, 6.7 ± 3.6) than benign IPMNs (mean ± standard deviation, 2.1 ± 1.0) (P < 0.001).

Conclusions: F-18 FDG PET/CT outperformed MDCT in detecting malignant IPMN.

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