Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010:(198):29-35.
doi: 10.1007/978-3-642-02062-9_2.

Estrogen signaling in the regulation of female reproductive functions

J K Findlay  1 , S H Liew, E R Simpson, K S Korach
Affiliations
Review

Estrogen signaling in the regulation of female reproductive functions

J K Findlay et al. Handb Exp Pharmacol. 2010.

Abstract

Estrogens influence fertility and infertility in animals. This chapter reviews the use of estrogen as a contraceptive through the regulation of its production and action. It is concluded that the use of specific agonists and antagonists of estrogen action that avoid the global and unwanted side effects of estrogen offers new potential methods of contraception.

PubMed Disclaimer

References

    1. Adlercreutz H. Phytoestrogens:epidemiology and a possible role in cancer protection. Environ Health Perspect. 1995;103(Suppl 7):103–112. - PMC - PubMed
    1. Britt KL, Findlay JK. Estrogen actions in the ovary revisited. J Endocrinol. 2002;175:269–276. - PubMed
    1. Britt KL, Findlay JK. Regulation of the phenotype of ovarian somatic cells by estrogen. Mol Cell Endocrinol. 2003;202:11–17. - PubMed
    1. Clyne CD, Speed CJ, Zhou J, Simpson ER. Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes. J Biol Chem. 2002;277:20591–20597. - PubMed
    1. Couse JF, Korach KS. Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev. 1999;20:358–417. - PubMed

Publication types

LinkOut - more resources