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. 2010 Sep;12(5):454-63.
doi: 10.1007/s11940-010-0082-9.

Triptans: where things stand

Alan K Cole  1 , Michael J Marmura
Affiliations

Triptans: where things stand

Alan K Cole et al. Curr Treat Options Neurol. 2010 Sep.

Abstract

Triptans, selective serotonin receptor agonists, were developed almost 20 years ago and represented a major breakthrough in the treatment of acute migraine attacks. Since then, the triptans have become first-line agents for most patients with migraine, both with and without aura, unless contraindicated. This article reviews the development of triptans, discusses reasons for their success or failure, and examines the limitations and controversies surrounding this class of medication.

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