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Randomized Controlled Trial
. 2011 Jul;28(7):626-7.
doi: 10.1136/emj.2009.089102. Epub 2010 Sep 15.

Early prehospital use of non-invasive ventilation improves acute respiratory failure in acute exacerbation of chronic obstructive pulmonary disease

Willi Schmidbauer  1 , Olaf Ahlers, Claudia Spies, Anke Dreyer, Georg Mager, Thoralf Kerner
Affiliations
Randomized Controlled Trial

Early prehospital use of non-invasive ventilation improves acute respiratory failure in acute exacerbation of chronic obstructive pulmonary disease

Willi Schmidbauer et al. Emerg Med J. 2011 Jul.

Abstract

Aim: To evaluate the use of prehospital non-invasive ventilation (NIV) in patients with acute exacerbation of chronic obstructive pulmonary disease.

Methods: 36 adult patients were treated by prehospital NIV or standard oxygen therapy.

Results: Prehospital NIV was described as feasible by the paramedics. Prehospital improvement of respiratory rate and dyspnoea was significantly better and the length of intensive care was significantly lower in NIV patients.

Conclusion: Prehospital NIV can be managed by a trained emergency team with high but sustainable workload. Dyspnoea and length of intensive care may be significantly reduced.

Clinical trial registration number: ISRCTN47620321.

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