Detection of the JAK2V617F mutation with the Ipsogen MutaScreen kit: absence of JAK2V617F does not mean absence of myeloproliferative neoplasm
- PMID: 20847214
- PMCID: PMC3173993
- DOI: 10.1182/blood-2010-06-289819
Detection of the JAK2V617F mutation with the Ipsogen MutaScreen kit: absence of JAK2V617F does not mean absence of myeloproliferative neoplasm
Comment on
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Failure of the Ipsogen MutaScreen kit to detect the JAK2 617V>F mutation in samples with additional rare exon 14 mutations: implications for clinical testing and report of a novel 618C>F mutation in addition to 617V>F.Blood. 2010 Apr 15;115(15):3175-6. doi: 10.1182/blood-2009-12-257501. Blood. 2010. PMID: 20395423 No abstract available.
References
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- Warshawsky I, Mularo F, Hren C, Jakubowski M. Failure of the Ipsogen MutaScreen kit to detect the JAK2 617V>F mutation in samples with additional rare exon 14 mutations: implications for clinical testing and report of a novel 618C>F mutation in addition to 617V>F [letter]. Blood. 2010;115(15):3175–3176. - PubMed
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- Murugesan G, Aboudola S, Szpurka H, et al. Identification of the JAK2 V617F mutation in chronic myeloproliferative disorders using FRET probes and melting curve analysis. Am J Clin Pathol. 2006;125(4):625–633. - PubMed
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- Biglia O, le Couedic J, Hermouet S, Hermitte F, Maroc N. Development and validation of new molecular diagnostic assays for the JAK2 V617F screening and quantification [abstract]. Association for Molecular Pathology 2007 Annual Meeting Abstracts. J Mol Diagn. 2007;9:669. Abstract H633.
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- Cankovic M, Whiteley L, Hawley RC, Zarbo RJ, Chitale D. Clinical performance of JAK2 V617F mutation detection assays in a molecular diagnostics laboratory: evaluation of screening and quantitation methods. Am J Clin Pathol. 2009;132(5):713–721. - PubMed
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