Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010;11(3):304-14.

The use of PROMIS and assessment center to deliver patient-reported outcome measures in clinical research

Richard C Gershon  1 , Nan Rothrock, Rachel Hanrahan, Michael Bass, David Cella
Affiliations

The use of PROMIS and assessment center to deliver patient-reported outcome measures in clinical research

Richard C Gershon et al. J Appl Meas. 2010.

Abstract

The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed as one of the first projects funded by the NIH Roadmap for Medical Research Initiative to re-engineer the clinical research enterprise. The primary goal of PROMIS is to build item banks and short forms that measure key health outcome domains that are manifested in a variety of chronic diseases which could be used as a "common currency" across research projects. To date, item banks, short forms and computerized adaptive tests (CAT) have been developed for 13 domains with relevance to pediatric and adult subjects. To enable easy delivery of these new instruments, PROMIS built a web-based resource (Assessment Center) for administering CATs and other self-report data, tracking item and instrument development, monitoring accrual, managing data, and storing statistical analysis results. Assessment Center can also be used to deliver custom researcher developed content, and has numerous features that support both simple and complicated accrual designs (branching, multiple arms, multiple time points, etc.). This paper provides an overview of the development of the PROMIS item banks and details Assessment Center functionality.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Instrument Characteristics
Figure 2
Figure 2
CAT Parameters
Figure 3
Figure 3
Item Statistics
Figure 4
Figure 4
CAT Preview
Figure 5
Figure 5
Item History
Figure 6
Figure 6
Questionnaire Summary Report Page 1
Figure 7
Figure 7
Questionnaire Summary Report Page 2
See this image and copyright information in PMC

References

    1. Andrich D. A rating formulation for ordered response categories. Psychometrika. 1978;43:561–573.
    1. Cella D, Gershon R, Lai JS, Choi S. The future of outcomes measurement: item banking, tailored short-forms, and computerized adaptive assessment. Quality of Life Research. 2007;16(Suppl. 1):133–141. - PubMed
    1. Cella D, Riley W, Stone AA, Rothrock N, Reeve BB, Yount S, et al. Initial item banks and first wave testing of the Patient Reported Outcomes Measurement Information System (PROMIS) network: 2005-2008. Journal of Clinical Epidemiology. in press. - PMC - PubMed
    1. Cella D, Victorson D, Nowinski C, Peterman A, Miller DM. The Neuro-QOL project: Using multiple methods to develop a HRQOL measurement platform to be used in clinical research across neurological conditions. Quality of Life Research. 2006;A-14:1353.
    1. Choi S. Firestar: Computerized adaptive testing simulation program for polytomous item response theory models. Applied Psychological Measurement. 2009;33(8):644–645.

LinkOut - more resources