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. 2009;4(2):82-87.
doi: 10.1159/000211368. Epub 2009 Apr 24.

Established and Suspected Risk Factors in Breast Cancer Aetiology

Alexander Kluttig  1 , Andrea Schmidt-Pokrzywniak
Affiliations

Established and Suspected Risk Factors in Breast Cancer Aetiology

Alexander Kluttig et al. Breast Care (Basel). 2009.

Abstract
in English, German

Although a current decline in breast cancer incidence and mortality is being observed, the disease continues to be the most common malignancy among women. Breast cancer is a worldwide public health problem that causes substantial personal and social burdens. While we do not yet know exactly what causes the disease, we know a large number of risk factors that are linked to breast cancer. In particular, hormonal factors seem to play a key role in the causation of the disease. The aim of this paper is to review the current knowledge of established and suspected risk factors of breast cancer from an epidemiologic point of view.

Trotz eines Rückgangs sowohl der Inzidenz als auch der Mortalität des Brustkrebses bleibt die Erkrankung die häufigste maligne Neubildung bei Frauen, verbunden mit erheblichen persönlichen Belastungen und gesellschaftlichen Kosten. Obwohl wir bisher nicht genau wissen, wie Brustkrebs entsteht, kennen wir doch eine Reihe von Risikofaktoren, die mit der Erkrankung in Verbindung stehen. Insbesondere hormonellen Faktoren kommt eine Schlüsselrolle in der Entstehung der Erkrankung zu. Ziel des vorliegenden Artikels ist die Zusammenfassung des aktuellen Kenntnisstandes zu etablierten und vermuteten Risikofaktoren des Brustkrebses aus epidemiologischer Sicht.

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Figures

Fig. 1
Fig. 1
Age-specific breast cancer incidence (per 100,000) (data derived from SEER Cancer Statistic Review, 2000–2004 [3]).
See this image and copyright information in PMC

References

    1. Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002: cancer incidence, mortality and prevalence worldwide. IARC CancerBase No 5, version 2.0. Lyon: IARC Press; 2004.
    1. Boyle P, Ferlay J. Cancer incidence and mortality in Europe, 2004. Ann Oncol. 2005;16:481–488. - PubMed
    1. Ries LAG, Melbert D, Krapcho M, Stinchcomb DG, Howlader N, Horner MJ, Mariotto A, Miller AB, Feuer EJ, Altekruse SF, Lewis DR, Clegg L, Eisner MP, Reichman M, Edwards BK: SEER Cancer Statistics Review, 1975–2005, National Cancer Institute, Bethesda, MD. http://seer cancer gov/csr/1975_2005/
    1. Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2000: Cancer incidence, mortality and prevalence worldwide. Lyon: IARC Press; 2001.
    1. Morris GJ, Mitchell EP. Higher incidence of aggressive breast cancers in African-American women: a review. J Natl Med Assoc. 2008;100:698–702. - PubMed