This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

. 2009 Sep-Oct:428:235-8.

doi: 10.1134/s1607672909050032.

Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds

S O Bachurin¹, A A Ustyugov, O Peters, T A Shelkovnikova, V L Buchman, N N Ninkina

Affiliations

PMID: 20848907
DOI: 10.1134/s1607672909050032

Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds

S O Bachurin et al. Dokl Biochem Biophys. 2009 Sep-Oct.

. 2009 Sep-Oct:428:235-8.

doi: 10.1134/s1607672909050032.

Authors

S O Bachurin¹, A A Ustyugov, O Peters, T A Shelkovnikova, V L Buchman, N N Ninkina

Affiliation

¹ Institute of Physiologically Active Compounds of the Russian Academy of Sciences, Chernogolovka, Russia. bachurin@ipac.ac.ru

PMID: 20848907
DOI: 10.1134/s1607672909050032

No abstract available

PubMed Disclaimer

Similar articles

Morphinan neuroprotection: new insight into the therapy of neurodegeneration.
Zhang W, Hong JS, Kim HC, Zhang W, Block ML. Zhang W, et al. Crit Rev Neurobiol. 2004;16(4):271-302. doi: 10.1615/critrevneurobiol.v16.i4.30. Crit Rev Neurobiol. 2004. PMID: 15862109 Review.
P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition.
Vázquez-Rosa E, Shin MK, Dhar M, Chaubey K, Cintrón-Pérez CJ, Tang X, Liao X, Miller E, Koh Y, Barker S, Franke K, Crosby DR, Schroeder R, Emery J, Yin TC, Fujioka H, Reynolds JD, Harper MM, Jain MK, Pieper AA. Vázquez-Rosa E, et al. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27667-27675. doi: 10.1073/pnas.2010430117. Epub 2020 Oct 21. Proc Natl Acad Sci U S A. 2020. PMID: 33087571 Free PMC article.
New Therapeutic Property of Dimebon as a Neuroprotective Agent.
Ustyugov A, Shevtsova E, Ashraf GM, Tarasov VV, Bachurin SO, Aliev G. Ustyugov A, et al. Curr Med Chem. 2018;25(39):5315-5326. doi: 10.2174/0929867323666160804122746. Curr Med Chem. 2018. PMID: 27494393 Review.
Beta-Synuclein-derived peptides with neuroprotective activity: an alternative treatment of neurodegenerative disorders?
Windisch M, Hutter-Paier B, Schreiner E, Wronski R. Windisch M, et al. J Mol Neurosci. 2004;24(1):155-65. doi: 10.1385/JMN:24:1:155. J Mol Neurosci. 2004. PMID: 15314265
Regulation of neuroinflammation by herbal medicine and its implications for neurodegenerative diseases. A focus on traditional medicines and flavonoids.
Suk K. Suk K. Neurosignals. 2005;14(1-2):23-33. doi: 10.1159/000085383. Neurosignals. 2005. PMID: 15956812 Review.

See all similar articles

Cited by

Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).
Ustyugov A, Shevtsova E, Bachurin S. Ustyugov A, et al. Mol Neurobiol. 2015 Oct;52(2):970-8. doi: 10.1007/s12035-015-9249-4. Epub 2015 Jun 30. Mol Neurobiol. 2015. PMID: 26123670 Review.
Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.
Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Bharadwaj PR, et al. Transl Psychiatry. 2013 Dec 3;3(12):e332. doi: 10.1038/tp.2013.97. Transl Psychiatry. 2013. PMID: 24301650 Free PMC article. Review.
Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice.
Shelkovnikova TA, Ustyugov AA, Millership S, Peters O, Anichtchik O, Spillantini MG, Buchman VL, Bachurin SO, Ninkina NN. Shelkovnikova TA, et al. Neurodegener Dis. 2011;8(6):430-7. doi: 10.1159/000324989. Epub 2011 May 12. Neurodegener Dis. 2011. PMID: 21576917 Free PMC article.
Testing the amyloid hypothesis of Alzheimer's disease in vivo.
Gandy S. Gandy S. Lancet Neurol. 2010 Apr;9(4):333-5. doi: 10.1016/S1474-4422(10)70055-7. Epub 2010 Feb 26. Lancet Neurol. 2010. PMID: 20189880 Free PMC article. No abstract available.
Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. Bharadwaj PR, et al. J Alzheimers Dis. 2012;32(4):949-67. doi: 10.3233/JAD-2012-120178. J Alzheimers Dis. 2012. PMID: 22903131 Free PMC article.

See all "Cited by" articles

References

1. Nat Neurosci. 2008 Mar;11(3):301-8 - PubMed
1. Mol Cell Biol. 2003 Nov;23(22):8233-45 - PubMed
1. Biochem Pharmacol. 2005 Apr 1;69(7):1001-8 - PubMed
1. Lancet. 2008 Jul 19;372(9634):207-15 - PubMed
1. CNS Spectr. 2007 Feb;12(2):113-6, 119-23 - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Ovid Technologies, Inc.
Medical
- MedlinePlus Health Information