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Case Reports
. 2010 Sep 17:10:109.
doi: 10.1186/1471-230X-10-109.

Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective

Peter T Kalogerinis  1 , John E Poulos, Andrew Morfesis, Anthony Daniels, Stavroula Georgakila, Thomas Daignualt, Alexandros G Georgakilas
Affiliations
Case Reports

Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective

Peter T Kalogerinis et al. BMC Gastroenterol. .

Abstract

Background: There is very small occurrence of adenocarcinoma in the small bowel. We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the molecular biology behind small bowel neoplasms and treatment options.

Case: The patient had a history of iron deficiency anemia and occult bleeding with extensive workup consisting of upper endoscopy, colonoscopy, capsule endoscopy, upper gastrointestinal series with small bowel follow through and push enteroscopy. Due to persistent abdominal pain and iron deficiency anemia the patient underwent push enteroscopy which revealed adenocarcinoma of the duodenum. The patient underwent en-bloc duodenectomy which revealed T3N1M0 adenocarcinoma of the 4th portion of the duodenum.

Conclusions: Primary duodenal carcinoma, although rare should be considered in the differential diagnosis of occult gastrointestinal bleeding when evaluation of the lower and upper GI tract is unremarkable. We discuss the current evaluation and management of this small bowel neoplasm.

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Figures

Figure 1
Figure 1
Endoscopic image of the small bowel neoplasm. The endoscopic image of the cancerous mass showing it's large irregular pattern and causing narrowing of the duodenum.
See this image and copyright information in PMC

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