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Comment
. 2010 Sep 17;142(6):839-41.
doi: 10.1016/j.cell.2010.08.036.

Influenza exits the cell without an ESCRT

Heinrich G Göttlinger  1
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Influenza exits the cell without an ESCRT

Heinrich G Göttlinger. Cell. .
Free article

Abstract

Many enveloped viruses depend on the membrane remodeling machinery of their host cells to complete their life cycle. In this issue, Rossman et al. (2010) now demonstrate that influenza virus possesses its own device for releasing nascent virus particles from the plasma membrane, the M2 proton-selective ion channel, which can substitute for the host cell's ESCRT pathway.

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