Review
doi: 10.12968/hmed.2010.71.8.77669.
Sorafenib in hepatocellular carcinoma
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- PMID: 20852487
- DOI: 10.12968/hmed.2010.71.8.77669
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Review
Sorafenib in hepatocellular carcinoma
Br J Hosp Med (Lond).
2010 Aug.
Abstract
Sorafenib, a small molecule multikinase inhibitor, is the standard of care in the USA and Europe for the treatment of advanced hepatocellular carcinoma. This article reviews its development from the basis of molecular hepatocarcinogenesis to phase III trials and discusses the future for sorafenib in hepatocellular carcinoma.
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