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. 2009 Mar;5(2):74-5.
doi: 10.1200/JOP.0922503.

When is standard treatment sufficiently active to make use of a placebo-controlled trial unethical?

Hans W Grünwald, Courtney D Storm, Geraldine M Jacobson

When is standard treatment sufficiently active to make use of a placebo-controlled trial unethical?

Hans W Grünwald et al. J Oncol Pract. 2009 Mar.

Abstract

Research has demonstrated that double blinding can lessen the potential for bias in study outcomes, such as perceiving a drug as more effective in the experimental arm of a study. Effective double-blinding techniques minimize the influence of investigator and patient expectations.

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