The influence of dendron's architecture on the "rigid" and "flexible" behaviour in binding DNA--a modelling study

Abstract

"Flexibility/rigidity" and "architecture" are cited among the Critical Nanoscale Design Parameters (CNDPs) that control the behaviour of dendritic molecules. We compare two different families of dendrons to explore the role played by architecture in influencing the ability of these molecules to optimize their surface to bind DNA-an indicator of rigid/flexible behaviour.