Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2011 Mar;5(1):63-6.
doi: 10.1007/s12105-010-0209-z. Epub 2010 Sep 21.

Ectopic thyroid presenting as a submandibular mass

Affiliations
Case Reports

Ectopic thyroid presenting as a submandibular mass

Joseli Assem Bersaneti et al. Head Neck Pathol. 2011 Mar.

Abstract

Although extremely rare, the presence of ectopic thyroid tissue in the submandibular region should be considered in the differential diagnosis of tissue masses in the cervical region. Diagnosis is confirmed by fine-needle aspiration biopsy and exclusion of malignancy should be confirmed by histopathologic analysis of the lesion. In general, surgery is the treatment of choice. A rare case of ectopic thyroid in the right submandibular region is reported; it was diagnosed after total thyroidectomy and successfully treated through surgery.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Scintigraphy with 99mTc-Pertechnetate in anterior projection of cervical region revealing uptake in the right submandibular region (arrow), corresponding to the anatomical location of the palpable nodule and on the neck midline, suggesting functioning thyroid tissues
Fig. 2
Fig. 2
Scintigraphies in anterior projection of cervical region, showing uptake in the right submandibular region and in neck midline, corresponding to anatomical location of palpable nodules. a Scintigraphy with 99mTc-Pertechnetate. b Scintigraphy with iodine-131
Fig. 3
Fig. 3
Fine-needle aspiration biopsy of right lateral cervical mass, showing a cytologic picture consistent with thyroid tissue (hematoxylin-eosin, original magnification 40×)
Fig. 4
Fig. 4
Photomicrograph of surgical specimen from submandibular region. Thyroid tissue showing different sizes of follicles with no signs of malignancy (hematoxylin-eosin, original magnification 20×)

References

    1. Choi JY, Kim JH. A case of an ectopic thyroid gland at the lateral neck masquerading as a metastatic papillary thyroid carcinoma. J Korean Med Sci. 2008;23(3):548–550. doi: 10.3346/jkms.2008.23.3.548. - DOI - PMC - PubMed
    1. Fumarola A, Trimboli P, Cavaliere R, et al. Thyroid papillary carcinoma arising in ectopic thyroid tissue within a neck branchial cyst. World J Surg Oncol. 2006;4:24. doi: 10.1186/1477-7819-4-24. - DOI - PMC - PubMed
    1. Huang TS, Chen HY. Dual thyroid ectopia with a normally located pretracheal thyroid gland: case report and literature review. Head Neck. 2007;29(9):885–888. doi: 10.1002/hed.20604. - DOI - PubMed
    1. Mace AT, McLaughlin I, Gibson IW, et al. Benign ectopic submandibular thyroid with a normotopic multinodular goitre. J Laryngol Otol. 2003;117(9):739–740. doi: 10.1258/002221503322334648. - DOI - PubMed
    1. Kousta E, Konstantinidis K, Michalakis C, et al. Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter and brief literature review. Hormones (Athens) 2005;4(4):231–234. - PubMed

Publication types

LinkOut - more resources