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Review
. 2010 Oct 12;103(8):1144-8.
doi: 10.1038/sj.bjc.6605901. Epub 2010 Sep 21.

MicroRNA in lung cancer

P-Y Lin  1 , S-L Yu, P-C Yang
Affiliations
Review

MicroRNA in lung cancer

P-Y Lin et al. Br J Cancer. .

Abstract

MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.

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Figures

Figure 1
Figure 1
Stratification of lung cancer based on microRNA information. NSCLC, non-small-cell lung cancer.
See this image and copyright information in PMC

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