Comment on

• Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.

  Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G. Pasquinelli AE, et al. Nature. 2000 Nov 2;408(6808):86-9. doi: 10.1038/35040556. Nature. 2000. PMID: 11081512
• Identification of novel genes coding for small expressed RNAs.

  Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. Lagos-Quintana M, et al. Science. 2001 Oct 26;294(5543):853-8. doi: 10.1126/science.1064921. Science. 2001. PMID: 11679670
• An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans.

  Lau NC, Lim LP, Weinstein EG, Bartel DP. Lau NC, et al. Science. 2001 Oct 26;294(5543):858-62. doi: 10.1126/science.1065062. Science. 2001. PMID: 11679671
• An extensive class of small RNAs in Caenorhabditis elegans.

  Lee RC, Ambros V. Lee RC, et al. Science. 2001 Oct 26;294(5543):862-4. doi: 10.1126/science.1065329. Science. 2001. PMID: 11679672
• Specificity of microRNA target selection in translational repression.

  Doench JG, Sharp PA. Doench JG, et al. Genes Dev. 2004 Mar 1;18(5):504-11. doi: 10.1101/gad.1184404. Epub 2004 Mar 10. Genes Dev. 2004. PMID: 15014042 Free PMC article.
• Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.

  Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Lim LP, et al. Nature. 2005 Feb 17;433(7027):769-73. doi: 10.1038/nature03315. Epub 2005 Jan 30. Nature. 2005. PMID: 15685193