Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Sep;18(9):430-6.
doi: 10.1007/BF03091810.

Endovascular stenting for aortic (re)coarctation in adults

E Moltzer  1 , J W Roos-Hesselink, S C Yap, J A A E Cuypers, A J J C Bogers, P P T de Jaegere, M Witsenburg
Affiliations

Endovascular stenting for aortic (re)coarctation in adults

E Moltzer et al. Neth Heart J. 2010 Sep.

Abstract

Objectives. Stenting for native and recurrent coarctation (COA) in adults has become an important therapeutic strategy. In this prospective observational study we evaluated the intermediate-term outcome of stent implantation for either native or recurrent (re)COA in adults.Methods. All adults who underwent stent implantation in our institution between January 2003 and December 2008 were included. Diagnosis of (re)COA was based upon a combination of clinical signs, noninvasive imaging or invasive gradient measurements. NuMED stents were implanted under general anaesthesia.Results. Twenty-four patients (50% male) underwent stent implantation for native (n=6) or reCOA (n=18) at a median age of 36 (18 to 60) years. There was significant improvement in pre- versus post-stent invasive systolic gradient (19 vs. 0 mmHg, p<0.001) and COA diameter (10 vs. 16 mm, p<0.001). Acute complications (12.5%) included death due to aortic rupture despite immediate successful coverage with a covered stent (n=1) and groin haematoma (n=2). During a median follow-up period of 33 (8 to 77) months (n=22), late complications occurred in three patients (13.6%): stent migration to the ascending aorta (n=1), pseudoaneurysm at the site of the initial stent (n=1), and occluded external iliac artery (n=1). Stent implantation did not reduce the need for antihypertensive medication or blood pressure at last follow-up. Conclusion. COA stenting results in a significant gradient decrease and increase in vessel diameter. However, serious complications do occur and hypertension remains in the majority of patients. (Neth Heart J 2010;18:430-6.).

Keywords: Aortic Coarctation; Catheter Intervention; Congenital Heart Disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A) Invasively measured peak systolic gradient before and after stent implantation. B) Minimum diameter at the side of the lesion before and after stent implantation. Box plots indicate the median, interquartile ranges, highest and lowest values; * p<0.001 vs. pre-stent.
See this image and copyright information in PMC

References

    1. Mullins CE, O'Laughlin MP, Vick GW, 3rd, Mayer DC, Myers TJ, Kearney DL, et al. Implantation of balloon-expandable intravascular grafts by catheterization in pulmonary arteries and systemic veins. Circulation. 1988;77:188-99. - PubMed
    1. O'Laughlin MP, Perry SB, Lock JE, Mullins CE. Use of endovascular stents in congenital heart disease. Circulation. 1991;83:1923-39. - PubMed
    1. Zabal C, Attie F, Rosas M, Buendia-Hernandez A, Garcia-Montes JA. The adult patient with native coarctation of the aorta: balloon angioplasty or primary stenting? Heart. 2003;89:77-83. - PMC - PubMed
    1. Marshall AC, Perry SB, Keane JF, Lock JE. Early results and medium-term follow-up of stent implantation for mild residual or recurrent aortic coarctation. Am Heart J. 2000;139:1054-60. - PubMed
    1. Harrison DA, McLaughlin PR, Lazzam C, Connelly M, Benson LN. Endovascular stents in the management of coarctation of the aorta in the adolescent and adult: one year follow up. Heart. 2001;85:561-6. - PMC - PubMed

LinkOut - more resources