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Review
. 2010 Oct:18 Suppl 3:S113-6.
doi: 10.1016/j.joca.2010.05.026.

Basic methods in histopathology of joint tissues

N Schmitz  1 , S Laverty, V B Kraus, T Aigner
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Free article
Review

Basic methods in histopathology of joint tissues

N Schmitz et al. Osteoarthritis Cartilage. 2010 Oct.
Free article

Abstract

Histological and histochemical methods are important tools in the evaluation of joint tissue samples for degenerative joint diseases, both in humans and in animal models. In this respect, standardized, simple, and reliable techniques are mandatory. This chapter describes five basic staining procedures appropriate for macroscopic (Indian ink) and histologic (HE/hematoxylin - eosin) visualization and scoring of cartilage proteoglycan and collagen content (toluidine blue/safranin O and picrosirius red/Goldner's trichrome).

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  • India ink and cartilage.
    Aspden RM. Aspden RM. Osteoarthritis Cartilage. 2011 Mar;19(3):332; author reply 333-5. doi: 10.1016/j.joca.2010.10.028. Epub 2011 Jan 5. Osteoarthritis Cartilage. 2011. PMID: 21215319 No abstract available.

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