Long noncoding RNAs add another layer to pre-mRNA splicing regulation
- PMID: 20864030
- DOI: 10.1016/j.molcel.2010.09.003
Long noncoding RNAs add another layer to pre-mRNA splicing regulation
Abstract
In this issue of Molecular Cell, Tripathi and coworkers (Tripathi et al., 2010) decode some of the functions of a long noncoding RNA MALAT1. They provide evidence that MALAT1 regulates alternative splicing by controlling the activity of the SR protein family of splicing factors.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation.Mol Cell. 2010 Sep 24;39(6):925-38. doi: 10.1016/j.molcel.2010.08.011. Mol Cell. 2010. PMID: 20797886 Free PMC article.
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