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Comment
. 2010 Sep 24;39(6):835-7.
doi: 10.1016/j.molcel.2010.09.006.

aMAGEing new players enter the RING to promote ubiquitylation

Kristen C Espantman  1 , Clodagh C O'Shea
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aMAGEing new players enter the RING to promote ubiquitylation

Kristen C Espantman et al. Mol Cell. .
Free article

Abstract

The MAGE proteins are best known as curious tumor-specific antigens. However, Doyle et al. (2010) reveal that MAGE proteins interact with RING proteins to promote ubiquitylation which provides important new insights into the physiological and pathological functions of this enigmatic family of proteins.

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