Review
doi: 10.1055/s-0030-1262882.
Epub 2010 Sep 23.
Modern determination of complement activation
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- PMID: 20865637
- DOI: 10.1055/s-0030-1262882
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Review
Modern determination of complement activation
Semin Thromb Hemost.
2010 Sep.
Abstract
Modern, that is, accurate determination of complement activation in vivo requires the simultaneous determination of both naive and activated complement proteins. This is best achieved by the use of native-restricted and neoepitope-specific monoclonal antibodies in sensitive enzyme-linked immunosorbent assays. Several confounding factors also have to be taken into account to allow a correct interpretation of the results.
© Thieme Medical Publishers.
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