Like parent, like child: inheritance of effector CD8+ T cell traits
- PMID: 20870171
- DOI: 10.1016/j.immuni.2010.09.005
Like parent, like child: inheritance of effector CD8+ T cell traits
Abstract
Beuneu et al. (2010) report that the amount of antigenic stimulation initially sensed by naive CD8(+) T cells can establish differentiation set points that are stably maintained in clonal progeny to promote functional diversity.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Visualizing the functional diversification of CD8+ T cell responses in lymph nodes.Immunity. 2010 Sep 24;33(3):412-23. doi: 10.1016/j.immuni.2010.08.016. Immunity. 2010. PMID: 20850354
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