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Case Reports
. 2010 Sep 13:2010:930190.
doi: 10.4061/2010/930190.

Mesalamine-induced myocarditis

Olivier Merceron  1 , Clement Bailly, Antoine Khalil, Florence Pontnau, Nadjib Hammoudi, Richard Dorent, Pierre-Louis Michel
Affiliations
Case Reports

Mesalamine-induced myocarditis

Olivier Merceron et al. Cardiol Res Pract. .

Abstract

Nowadays mesalamine is a common treatment for Crohn's disease and hypersensitive reactions to this product have been reported. Yet there is limited information concerning mesalamine-induced myocarditis and its mechanism is not known. We described a case of mesalamine-induced myocarditis in Crohn's disease of the colon.

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Figures

Figure 1
Figure 1
Cardiac MR shows on the late enhancement sequence, transmural enhancement of the basal interventricular septum ((a) short axis, (b) long axis).
Figure 2
Figure 2
Course of systemic inflammation and troponin after mesalamine re-introduction in a patient with mesalamine induced myocarditis in Crohn's disease of the colon.
See this image and copyright information in PMC

References

    1. García-Ferrer L, Estornell J, Palanca V. Myocarditis by mesalazine with cardiac magnetic resonance imaging. European Heart Journal. 2009;30(8):p. 1015. - PubMed
    1. Doganay L, Akinci B, Pekel N, Simsek I, Akpinar H. Mesalazine-induced myopericarditis in a patient with ulcerative colitis. International Journal of Colorectal Disease. 2006;21(2):199–200. - PubMed
    1. Stelts S, Taylor MH, Nappi J, Van Bakel AB. Mesalamine-associated hypersensitivity myocarditis in ulcerative colitis. Annals of Pharmacotherapy. 2008;42(6):904–905. - PubMed
    1. Kirstensen KS, Høegholm A, Bohr L, Friis S. Fatal myocarditis associated with mesalazine. Lancet. 1990;335(8689):p. 605. - PubMed
    1. García-Morán S, Sáez-Royuela F, Pérez-Alvarez J-C, Gento E, Téllez J. Myopericarditis and mitral insufficiency associated with ulcerative colitis treated with mesalazine. Inflammatory Bowel Diseases. 2006;12(4):334–335. - PubMed

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