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Review
. 2010 Dec;14(12):2721-8.
doi: 10.1111/j.1582-4934.2010.01178.x.

Proteomics and syndrome of Chinese medicine

Chuan-Li Lu  1 , Xiao-Ying Qv, Jian-Guo Jiang
Affiliations
Review

Proteomics and syndrome of Chinese medicine

Chuan-Li Lu et al. J Cell Mol Med. 2010 Dec.

Abstract

Syndrome of Chinese medicine is an understanding of the regularity of disease occurrence and development and its performance of symptoms. Syndrome is the key to recognize diseases and the foundation to treat them. However, because of the complexity of the concept and the limitation of present investigations, the research of syndrome is hard to go further. Proteomics has been received extensive attention in the area of medical diagnosis and drug development. In the holistic and systemic context, proteomics have a convergence with traditional Chinese medicine (TCM) syndrome, which could overcome the one-sidedness and singleness of TCM and avoid the complication and tedious processes. Chinese medicine has a wealth of experience and proteomics has a substantial research potential, the integration of the two aspects will bring a great enhancement of our knowledge of disease.

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Figures

Fig 1
Fig 1
The important steps in the proteomics work flow. Two-dimensional gel electrophoresis is the central tool for displaying the proteome. Proteins are separated on the basis of charge in the first dimension and molecular mass in the second. The emerging technology of mass spectrometry-based quantitative proteomics provides a powerful tool to systematically and quantitatively assess quantitative differences in protein profiles of different samples and is become an important component of biomedical and clinical research.
Fig 2
Fig 2
The relevant disciplines involved in the articles themed by proteomics published during 1997–2009. A total of 21,111 articles were retrieved on 22 June 2010 by searching the theme of Proteomics through the Web of Science database in the ISI Web of Knowledge, then analysed by subject area and sorted by the number of articles. The top 21 names of disciplines and the number of related articles are listed here.
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Publication types