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Comment
. 2010 Oct 5;107(40):17065-6.
doi: 10.1073/pnas.1012547107. Epub 2010 Sep 27.

Designer drugs for discerning bugs

Stephen Douthwaite  1
Affiliations
Comment

Designer drugs for discerning bugs

Stephen Douthwaite. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Secondary structure of the peptidyl transferase center in E. coli 23S rRNA. The site of erythromycin resistance methylation at A2058 is shown in red. Key nucleotide interactions (blue) that support antibiotic binding are the same in T. thermophilus but different in H. halobium rRNA. D. radiodurans rRNA has C752 (21) and thus lacks the 752–2609 bp onto which the telithromycin heterocycles would stack.
See this image and copyright information in PMC

Comment on

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