KRAS mutational analysis for colorectal cancer. Application: pharmacogenomic
- PMID: 20877448
- PMCID: PMC2940138
- DOI: 10.1371/currents.RRN1175
KRAS mutational analysis for colorectal cancer. Application: pharmacogenomic
Abstract
KRAS mutational analysis is a genetic test used in clinical practice for determining the status of the KRAS gene (wild type or mutant) in tumors from patients with metastatic colorectal cancer (CRC). Persons whose tumors are wild type may respond to therapies cetuximab (Erbitux) or panitumumab (Vectibix).
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