Androgen deprivation therapy for prostate cancer-review of indications in 2010
- PMID: 20882131
- PMCID: PMC2935708
- DOI: 10.3747/co.v17i0.698
Androgen deprivation therapy for prostate cancer-review of indications in 2010
Abstract
The discovery of androgen deprivation therapy (ADT) has been one of the most important advances in the treatment of prostate cancer. Here, the indications for the use of ADT are reviewed, together with the data supporting each indication. The settings for ADT use include cytoreduction; combined ADT and radiotherapy; pathologic node-positive disease; and recurrent, metastatic, or progressive prostate cancer.
Keywords: Androgen antagonists; combined-modality therapy; disease progression; hormonal anti-neoplastic agents; orchiectomy; prostatectomy; prostatic neoplasms; radiotherapy.
References
-
- Klotz L, Boccon–Gibod L, Shore ND, et al. The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase iii study in patients with prostate cancer. BJU Int. 2008;102:1531–8. - PubMed
-
- D’Amico AV, Whittington R, Malkowicz SB, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280:969–74. - PubMed
-
- Nag S, Beyer D, Friedland J, Grimm P, Nath R. American Brachytherapy Society (abs) recommendations for transperineal permanent brachytherapy of prostate cancer. Int J Radiat Oncol Biol Phys. 1999;44:789–99. - PubMed
-
- Whittington R, Broderick GA, Arger P, et al. The effect of androgen deprivation on the early changes in prostate volume following transperineal ultrasound guided interstitial therapy for localized carcinoma of the prostate. Int J Radiat Oncol Biol Phys. 1999;44:1107–10. - PubMed
LinkOut - more resources
Full Text Sources
