IDH1 and IDH2 mutations in myeloid neoplasms--novel paradigms and clinical implications
- PMID: 20884716
- PMCID: PMC2948084
- DOI: 10.3324/haematol.2010.030015
IDH1 and IDH2 mutations in myeloid neoplasms--novel paradigms and clinical implications
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Comment on
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IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.Haematologica. 2010 Oct;95(10):1668-74. doi: 10.3324/haematol.2010.025494. Epub 2010 May 21. Haematologica. 2010. PMID: 20494930 Free PMC article.
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Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial.Haematologica. 2010 Oct;95(10):1754-61. doi: 10.3324/haematol.2009.019182. Epub 2010 May 21. Haematologica. 2010. PMID: 20494931 Free PMC article. Clinical Trial.
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IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody.Haematologica. 2010 Oct;95(10):1797-8. doi: 10.3324/haematol.2010.024430. Epub 2010 Jun 9. Haematologica. 2010. PMID: 20534697 Free PMC article. No abstract available.
References
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- Tefferi A, Skoda R, Vardiman JW. Myeloproliferative neoplasms: contemporary diagnosis using histology and genetics. Nat Rev Clin Oncol. 2009;6(11):627–37. - PubMed
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- Dohner H, Estey EH, Amadori S, Appelbaum FR, Buchner T, Burnett AK, et al. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood. 2010;115(3):453–74. - PubMed
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