Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Sep;83(3):135-7.

Five classic articles in somatic cell reprogramming

Affiliations
Review

Five classic articles in somatic cell reprogramming

In-Hyun Park. Yale J Biol Med. 2010 Sep.

Abstract

Research on somatic cell reprogramming has progressed significantly over the past few decades, from nuclear transfer into frogs' eggs in 1952 to the derivation of human-induced pluripotent stem (iPS) cells in the present day. In this article, I review five landmark papers that have laid the foundation for current efforts to apply somatic cell reprogramming in the clinic.

PubMed Disclaimer

Similar articles

Cited by

  • Dental pulp tissue engineering.
    Demarco FF, Conde MC, Cavalcanti BN, Casagrande L, Sakai VT, Nör JE. Demarco FF, et al. Braz Dent J. 2011;22(1):3-13. doi: 10.1590/s0103-64402011000100001. Braz Dent J. 2011. PMID: 21519641 Free PMC article. Review.

References

    1. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663–676. - PubMed
    1. Briggs R, King TJ. Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs’ Eggs. Proc Natl Acad Sci USA. 1952;38(5):455–463. - PMC - PubMed
    1. Gurdon JB, Elsdale TR, Fischberg M. Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei. Nature. 1958;182(4627):64–65. - PubMed
    1. Stevens LC, Little CC. Spontaneous Testicular Teratomas in an Inbred Strain of Mice. Proc Natl Acad Sci USA. 1954;40(11):1080–1087. - PMC - PubMed
    1. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292(5819):154–156. - PubMed

MeSH terms

LinkOut - more resources