Waste management and adult neurogenesis
- PMID: 20887944
- DOI: 10.1016/j.stem.2010.09.008
Waste management and adult neurogenesis
Abstract
Dying cells are common in adult neurogenic niches, but how these cells are cleared remains uncertain. In this issue of Cell Stem Cell, Sierra et al. (2010) show that unactivated microglia assume the role of waste managers to eliminate cellular debris from apoptosing newborn cells in the hippocampus.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis.Cell Stem Cell. 2010 Oct 8;7(4):483-95. doi: 10.1016/j.stem.2010.08.014. Cell Stem Cell. 2010. PMID: 20887954 Free PMC article.
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