Expansion of human cord blood hematopoietic stem cells for transplantation

doi:10.1016/j.stem.2010.09.001

. 2010 Oct 8;7(4):427-8.

doi: 10.1016/j.stem.2010.09.001.

Expansion of human cord blood hematopoietic stem cells for transplantation

Song Chou¹, Pat Chu, William Hwang, Harvey Lodish

Affiliations

PMID: 20887947
PMCID: PMC2962561
DOI: 10.1016/j.stem.2010.09.001

Expansion of human cord blood hematopoietic stem cells for transplantation

Song Chou et al. Cell Stem Cell. 2010.

. 2010 Oct 8;7(4):427-8.

doi: 10.1016/j.stem.2010.09.001.

Authors

Song Chou¹, Pat Chu, William Hwang, Harvey Lodish

Affiliation

¹ Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

PMID: 20887947
PMCID: PMC2962561
DOI: 10.1016/j.stem.2010.09.001

Abstract

A recent Science paper reported a purine derivative that expands human cord blood hematopoietic stem cells in culture (Boitano et al., 2010) by antagonizing the aryl hydrocarbon receptor. Major problems need to be overcome before ex vivo HSC expansion can be used clinically.

PubMed Disclaimer

Cited by

Influence of neonatal gender on cord blood CD34⁺ cell amplification and gene expression.
Zhou L, Che Z, Zhang X, Zhou P, Li X, Xu X, Shi Q, Li D, Ju X. Zhou L, et al. Exp Ther Med. 2019 Jul;18(1):105-118. doi: 10.3892/etm.2019.7549. Epub 2019 May 7. Exp Ther Med. 2019. PMID: 31258643 Free PMC article.
A motif in LILRB2 critical for Angptl2 binding and activation.
Deng M, Lu Z, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, Zhang CC. Deng M, et al. Blood. 2014 Aug 7;124(6):924-35. doi: 10.1182/blood-2014-01-549162. Epub 2014 Jun 4. Blood. 2014. PMID: 24899623 Free PMC article.
Ex vivo expansion of human hematopoietic stem and progenitor cells.
Dahlberg A, Delaney C, Bernstein ID. Dahlberg A, et al. Blood. 2011 Jun 9;117(23):6083-90. doi: 10.1182/blood-2011-01-283606. Epub 2011 Mar 23. Blood. 2011. PMID: 21436068 Free PMC article. Review.
Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions.
Liu H, Rich ES, Godley L, Odenike O, Joseph L, Marino S, Kline J, Nguyen V, Cunningham J, Larson RA, del Cerro P, Schroeder L, Pape L, Stock W, Wickrema A, Artz AS, van Besien K. Liu H, et al. Blood. 2011 Dec 8;118(24):6438-45. doi: 10.1182/blood-2011-08-372508. Epub 2011 Oct 5. Blood. 2011. PMID: 21976674 Free PMC article. Clinical Trial.
Combination of a haploidentical SCT with an unrelated cord blood unit: a single-arm prospective study.
Chen J, Wang RX, Chen F, Sun AN, Qiu HY, Jin ZM, Tang XW, Han Y, Fu ZZ, He GS, Miao M, Ma X, Wu DP. Chen J, et al. Bone Marrow Transplant. 2014 Feb;49(2):206-11. doi: 10.1038/bmt.2013.154. Epub 2013 Oct 21. Bone Marrow Transplant. 2014. PMID: 24141650

See all "Cited by" articles

References

1. Ahrlund-Richter L, et al. Cell Stem Cell. 2009;4:20–26. - PubMed
1. Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, et al. Science. 2010 doi: 10.1126/science.1191536. - DOI - PMC - PubMed
1. Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Nat Med. 2010;16:232–236. - PMC - PubMed
1. Foeken LM, Green A, Hurley CK, Marry E, Wiegand T, Oudshoorn M. Bone Marrow Transplant. 2010;45:811–818. - PubMed
1. Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, et al. Nat Med. 2010;16:475–482. - PMC - PubMed

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions

Grants and funding

R01 DK067356/DK/NIDDK NIH HHS/United States

LinkOut - more resources

Full Text Sources
Other Literature Sources
- The Lens - Patent Citations Database
Medical
- MedlinePlus Health Information

[1] Ahrlund-Richter L, et al. Cell Stem Cell. 2009;4:20–26. - PubMed

[2] Ahrlund-Richter L, et al. Cell Stem Cell. 2009;4:20–26. - PubMed

[3] Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, et al. Science. 2010 doi: 10.1126/science.1191536. - DOI - PMC - PubMed

[4] Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, et al. Science. 2010 doi: 10.1126/science.1191536. - DOI - PMC - PubMed

[5] Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Nat Med. 2010;16:232–236. - PMC - PubMed

[6] Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID. Nat Med. 2010;16:232–236. - PMC - PubMed

[7] Foeken LM, Green A, Hurley CK, Marry E, Wiegand T, Oudshoorn M. Bone Marrow Transplant. 2010;45:811–818. - PubMed

[8] Foeken LM, Green A, Hurley CK, Marry E, Wiegand T, Oudshoorn M. Bone Marrow Transplant. 2010;45:811–818. - PubMed

[9] Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, et al. Nat Med. 2010;16:475–482. - PMC - PubMed

[10] Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, et al. Nat Med. 2010;16:475–482. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Expansion of human cord blood hematopoietic stem cells for transplantation

Affiliation

Expansion of human cord blood hematopoietic stem cells for transplantation

Authors

Affiliation

Abstract

Similar articles

Cited by

References

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Abstract

Similar articles

Cited by

References

MeSH terms

Substances

Related information

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical