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Meta-Analysis
. 2010 Dec 1;68(11):982-90.
doi: 10.1016/j.biopsych.2010.07.021.

Attention bias modification treatment: a meta-analysis toward the establishment of novel treatment for anxiety

Yuko Hakamata  1 , Shmuel Lissek, Yair Bar-Haim, Jennifer C Britton, Nathan A Fox, Ellen Leibenluft, Monique Ernst, Daniel S Pine
Affiliations
Meta-Analysis

Attention bias modification treatment: a meta-analysis toward the establishment of novel treatment for anxiety

Yuko Hakamata et al. Biol Psychiatry. .

Erratum in

  • Biol Psychiatry. 2012 Sep 1;72(5):429

Abstract

Background: Attention Bias Modification Treatment (ABMT) is a newly emerging, promising treatment for anxiety disorders. Although recent randomized control trials (RCTs) suggest that ABMT reduces anxiety, therapeutic effects have not been summarized quantitatively.

Methods: Standard meta-analytic procedures were used to summarize the effect of ABMT on anxiety. With MEDLINE, January 1995 to February 2010, we identified RCTs comparing the effects on anxiety of ABMT and quantified effect sizes with Hedge's d.

Results: Twelve studies met inclusion criteria, including 467 participants from 10 publications. Attention Bias Modification Treatment produced significantly greater reductions in anxiety than control training, with a medium effect (d = .51 [corrected] (p < .001). Age and gender did not moderate the effect of ABMT on anxiety, whereas several characteristics of the ABMT training did.

Conclusions: Attention Bias Modification Treatment shows promise as a novel treatment for anxiety. Additional RCTs are needed to fully evaluate the degree to which these findings replicate and apply to patients. Future work should consider the precise role for ABMT in the broader anxiety-disorder therapeutic armamentarium.

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Conflict of interest statement

Financial Disclosures All authors report no biomedical financial interests or potential conflicts of interest.

Figures

Figure 1
Figure 1
Two stimuli differing in emotional valence (threat or non-threat) are presented at the same time usually for 500ms, and then followed by a probe (i.e. colon). In the classic dot probe task to measure an attention bias, a probe appears shortly after either of the locations that the two stimuli were presented, with the same frequencies (i.e. 50%, trials A and B are equally mixed). On the other hand, in the modified dot probe task (i.e. Attention Bias Modification Treatment), a probe always appears in the location of neutral stimulus (i.e. 100%, only B trials).
Figure 2
Figure 2
Size of round circle reflects sample size
Figure 3
Figure 3
Spearman’s r = 0.75, p = 0.052.
See this image and copyright information in PMC

Comment in

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