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. 1978 May;20(2):575-7.
doi: 10.1128/iai.20.2.575-577.1978.

Properties of an Escherichia coli cytotoxin

J Konowalchuk, N Dickie, S Stavric, J I Speirs

Properties of an Escherichia coli cytotoxin

J Konowalchuk et al. Infect Immun. 1978 May.

Abstract

Isoelectric focusing of a heat-labile cytotoxin of Escherichia coli H30 revealed the presence of two molecular variants, pI 7.2 and a comparatively small quantity of pI 6.8. Predominant component pI 7.2 had a molecular weight of 28,000, induced some fluid accumulation in rabbit ileal loops, and showed no morphological response in Y-1 cells but a strong cytotoxic effect on Vero cells.

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