doi: 10.7164/antibiotics.31.456.
Cyclic phosphates of formycin
- PMID: 209007
- DOI: 10.7164/antibiotics.31.456
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Cyclic phosphates of formycin
J Antibiot (Tokyo).
1978 May.
Free article
Abstract
The syntheses of N1- and N2-isopropylformycin (10, 11), formycin 3',5'-cyclic and 2',3'-cyclic phosphate (3,7) and their N-methyl and N-isopropyl derivatives (13, 15, 19, 23) are described. It was observed that substitution at N1 or N2 with a bulky alkyl group or cyclic phosphorylation of the ribose moiety made formycin resistant to adenosine deaminase.
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