Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Sep-Oct;39(5):510-8.
doi: 10.1111/j.1552-6909.2010.01172.x.

A historical overview of preeclampsia-eclampsia

Mandy J Bell  1
Affiliations

A historical overview of preeclampsia-eclampsia

Mandy J Bell. J Obstet Gynecol Neonatal Nurs. 2010 Sep-Oct.

Abstract

Preeclampsia is a hypertensive, multisystem disorder of pregnancy whose etiology remains unknown. Although management is evidence-based, preventative measures/screening tools are lacking, treatment remains symptomatic, and delivery remains the only cure. Past hypotheses/scientific contributions have influenced current understanding of preeclampsia pathophysiology and guided management strategies and classification criteria. To provide insight into how past hypotheses/scientific contributions have shaped current practice trends, this article provides a historical overview of preeclampsia-eclampsia.

PubMed Disclaimer

References

    1. American College of Obstetricians and Gynecologists. ACOG practice bulletin: Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. Obstetrics & Gynecology. 2002;99(1):159–167. - PubMed
    1. Brosens IA, Robertson WB, Dixon HG. The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Annu. 1972;1:177–191. - PubMed
    1. Brosens I, Robertson WB, Dixon HG. The physiological response of the vessels of the placental bed to normal pregnancy. Journal Path Bacteriol. 1967;93(2):569–579. - PubMed
    1. Burton JL, editor. Six hundred miseries’: The seventeenth century womb. 2005.
    2. Riviere L. In: Book 15 of ‘The Practice of Physick’. Culpeper N, translator. London: 1678. Original work published 1655.
    1. Caniggia I, Taylor CV, Ritchie JW, Lye SJ, Letarte M. Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants. Endocrinology. 1997;138(11):4977–4988. - PubMed

Publication types