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Review
. 2010 Sep 30:8:115.
doi: 10.1186/1477-7827-8-115.

Determinants of menarche

Olga Karapanou  1 , Anastasios Papadimitriou
Affiliations
Review

Determinants of menarche

Olga Karapanou et al. Reprod Biol Endocrinol. .

Abstract

Menarche is a milestone in a woman's life as it denotes the start of reproductive capacity. Aim of this report is to review the recent developments and the current knowledge in the neuroendocrinology of pubertal onset and the factors, genetic and environmental, that influence menarcheal age. We also review the implications of early or late menarcheal age on a young woman's life.

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Figures

Figure 1
Figure 1
Stimulatory (arrow) and inhibitory (blind-ended arrow) effectors of GnRH pulsatile secretion. mTOR (mammalian target of rapamycin)
See this image and copyright information in PMC

References

    1. Heidi DH. Yearbook of Phys Anthropol. 1. Vol. 29. 1986. Menarcheal age in Europe; pp. 81–112. - DOI
    1. Tanner JM. Foetus into Man. 2. Ware: Castlemead Publications; 1989.
    1. Dan TC, Roberts DF. Menarcheal age in University of Warwick young women. J Biol Sci. 1993;25:531–538. - PubMed
    1. Lindgren GW, Degertors IL, Fredrikson A, Loukili A, Mannerfeldt R, Nordin M, Palm K, Petterson M, Sundstrand G, Sylvan E. Menarche 1990 in Stockholm schoolgirls. Acta Paediatr Scand. 1991;80:953–955. doi: 10.1111/j.1651-2227.1991.tb11758.x. - DOI - PubMed
    1. Morris JA, Jordan CL, Breedlove SM. Sexual differentiation of the vertebrate nervous system. Nat Neurosci. 2004;7:1034–1039. doi: 10.1038/nn1325. - DOI - PubMed

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