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Clinical Trial
. 2011 Feb;17(1):4-10.
doi: 10.1111/j.1600-0846.2010.00464.x.

Dermatological feasibility of multimodal facial color imaging modality for cross-evaluation of facial actinic keratosis

Youngwoo Bae  1 , Taeyoon Son, J Stuart Nelson, Jae-Hong Kim, Eung Ho Choi, Byungjo Jung
Affiliations
Clinical Trial

Dermatological feasibility of multimodal facial color imaging modality for cross-evaluation of facial actinic keratosis

Youngwoo Bae et al. Skin Res Technol. 2011 Feb.

Abstract

Background/purpose: Digital color image analysis is currently considered as a routine procedure in dermatology. In our previous study, a multimodal facial color imaging modality (MFCIM), which provides a conventional, parallel- and cross-polarization, and a fluorescent color image, was introduced for objective evaluation of various facial skin lesions. This study introduces a commercial version of MFCIM, DermaVision-PRO, for routine clinical use in dermatology and demonstrates its dermatological feasibility for cross-evaluation of skin lesions.

Methods/results: Sample images of subjects with actinic keratosis or non-melanoma skin cancers were obtained at four different imaging modes. Various image analysis methods were applied to cross-evaluate the skin lesion and, finally, to extract valuable diagnostic information. DermaVision-PRO is potentially a useful tool as an objective macroscopic imaging modality for quick prescreening and cross-evaluation of facial skin lesions.

Conclusion: DermaVision-PRO may be utilized as a useful tool for the cross-evaluation of widely distributed facial skin lesions and as an efficient database management of patient information.

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Figures

Figure 1
Figure 1
(a) DermaVision-PRO consists of an imaging box (1), display panel (2), and software control panel (3). (b) The imaging box consists of a flash white light (4), a digital color camera (5), three-position linear polarizer holder (6), and four UV-A lamps (7). Linearly polarized light (8) and UV-A radiation (9) incident to human face on head-positioning device (10) are reflected back to the digital color camera.
Figure 2
Figure 2
(a) “Single Image Analysis Window” provides a full-scale image for close-up investigation of processed images which stem from different image channels. (b) “Total Image Analysis Window” provides comparison of images before and after treatment.
Figure 3
Figure 3
Multimodal images of a female subject with fluorescent actinic (solar) keratosis (AK) on facial skin lesions: (a) melanin index image; (b) erythma index image computed from CPCI; (c) fluorescent color image (FCI); (d) polarization image (PI).
Figure 4
Figure 4
Multimodal images of a male subject with non-fluorescent actinic (solar) keratosis (AK) on facial skin lesions: (a) melanin index image; (b) erythma index image computed from CPCI; (c) fluorescent color image (FCI); (d) polarization image (PI).
Figure 5
Figure 5
Comparison of the fluorescent intensity and E.I. on AK lesions and surrounding normal skin regions in the fluorescent group.
See this image and copyright information in PMC

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