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Meta-Analysis
. 2010 Oct;10(10):1529-36.
doi: 10.1586/ern.10.94.

Brain tumor location and psychiatric symptoms: is there any association? A meta-analysis of published case studies

Subramoniam Madhusoodanan  1 , Mark G A Opler, Despina Moise, Jessica Gordon, Deepa M Danan, Abhishek Sinha, Ramesh P Babu
Affiliations
Meta-Analysis

Brain tumor location and psychiatric symptoms: is there any association? A meta-analysis of published case studies

Subramoniam Madhusoodanan et al. Expert Rev Neurother. 2010 Oct.

Abstract

A meta-analytic study of reports of brain tumors and psychiatric symptoms for the past 50 years was conducted to examine potential associations between tumor location and psychiatric symptoms. Results demonstrated that there is a statistically significant association between anorexia symptoms and hypothalamic tumors. For the rest of the brain regions a statistically significant association could not be definitively determined. However, several of the regions demonstrated an increased likelihood of associated symptoms when compared with other regions. The methodological limitations of this analysis are discussed.

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