Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Nov 5;12(21):4888-91.
doi: 10.1021/ol1020527.

Ruthenium-catalyzed tertiary amine formation from nitroarenes and alcohols

Chao Feng  1 , Yong Liu, Shengming Peng, Qi Shuai, Guojun Deng, Chao-Jun Li
Affiliations

Ruthenium-catalyzed tertiary amine formation from nitroarenes and alcohols

Chao Feng et al. Org Lett. .

Abstract

A highly selective ruthenium-catalyzed C-N bond formation was developed by using the hydrogen-borrowing strategy. Various tertiary amines were obtained efficiently from nitroarenes and primary alcohols. The reaction tolerates a wide range of functionalities. A tentative mechanism was proposed for this direct amination reaction of alcohols with nitroarenes.

PubMed Disclaimer

Publication types

LinkOut - more resources