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. 2011 May;50(1):49-68.
doi: 10.1007/s12026-010-8173-y.

On the logic of restrictive recognition of peptide by the T-cell antigen receptor

Melvin Cohn  1
Affiliations

On the logic of restrictive recognition of peptide by the T-cell antigen receptor

Melvin Cohn. Immunol Res. 2011 May.

Abstract

This essay provides an analysis of the inadequacy of the current view of restrictive recognition of peptide by the T-cell antigen receptor. A competing model is developed, and the experimental evidence for the prevailing model is reinterpreted in the new framework. The goal is to contrast the two models with respect to their consistency, coverage of the data, explanatory power, and predictability.

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Conflict of interest statement

Conflict of interest The author has no financial conflict of interest.

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