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Comparative Study
. 2011 Apr;40(2):137-43.
doi: 10.1016/j.jgyn.2010.08.005. Epub 2010 Oct 8.

[Comparison between two analgesic protocols on IVF success rates]

[Article in French]
O Mialon  1 , J Delotte, P Lehert, M Donzeau, M Drici, V Isnard, A Bongain
Affiliations
Free article
Comparative Study

[Comparison between two analgesic protocols on IVF success rates]

[Article in French]
O Mialon et al. J Gynecol Obstet Biol Reprod (Paris). 2011 Apr.
Free article

Abstract

Objectives: Analgesic protocols administered before a follicular puncture under local anesthesia are well tolerated when using NSAIDs, but we still do not know their possible impacts on in vitro fertilization (IVF) outcomes.

Material and methods: A retrospective monocentric study using two consecutive temporal cohorts of patients was conducted to compare two analgesic protocols: paracetamol/alprazolam (P/A), then nefopam/ketoprofen (N/K).

Results: We demonstrated that biochemical pregnancy rate and the others outcomes of IVF are not significantly influenced by the type of analgesic protocol used.

Conclusion: The protocol N/K enhances patient comfort without jeopardizing the IVF success rates.

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