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Review
. 2010 Dec;24(4):871-84, vii.
doi: 10.1016/j.idc.2010.07.006.

Cholangiocarcinoma: new insights into disease pathogenesis and biology

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Review

Cholangiocarcinoma: new insights into disease pathogenesis and biology

Chiara Braconi et al. Infect Dis Clin North Am. 2010 Dec.

Abstract

Cholangiocarcinomas are rare malignant tumors whose incidence is increasing worldwide. Risk factors for this malignancy include both infectious and non-infectious diseases characterized by chronic inflammation of the bile duct epithelia. Diagnosis of these cancers remains difficult because of the lack of sensitive diagnostic tests. The prognosis is poor probably because of the lack of effective treatments for unresectable cancer.

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Figures

Figure 1
Figure 1
MRI liver showing a multifocal, poorly differentiated intrahepatic cholangiocarcinoma with vascular invasion.

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