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. 2010 Oct 12;75(15):1362-9.
doi: 10.1212/WNL.0b013e3181f735a7.

Epidemiology of Parkinson disease in the city of Kolkata, India: a community-based study

S K Das  1 , A K Misra, B K Ray, A Hazra, M K Ghosal, A Chaudhuri, T Roy, T K Banerjee, D K Raut
Affiliations

Epidemiology of Parkinson disease in the city of Kolkata, India: a community-based study

S K Das et al. Neurology. .

Abstract

Objective: No well-designed longitudinal study on Parkinson disease (PD) has been conducted in India. Therefore, we planned to determine the prevalence, incidence, and mortality rates of PD in the city of Kolkata, India, on a stratified random sample through a door-to-door survey.

Method: This study was undertaken between 2003 to 2007 with a validated questionnaire by a team consisting of 4 trained field workers in 3 stages. Field workers screened the cases, later confirmed by a specialist doctor. In the third stage, a movement disorders specialist undertook home visits and reviewed all surviving cases after 1 year from last screening. Information on death was collected through verbal autopsy. A nested case-control study (1:3) was also undertaken to determine putative risk factors. The rates were age adjusted to the World Standard Population.

Result: A total population of 100,802 was screened. The age-adjusted prevalence rate (PR) and average annual incidence rate were 52.85/100,000 and 5.71/100,000 per year, respectively. The slum population showed significantly decreased PR with age compared with the nonslum population. The adjusted average annual mortality rate was 2.89/100,000 per year. The relative risk of death was 8.98. The case-control study showed that tobacco chewing protected and hypertension increased PD occurrence.

Conclusion: This study documented lower prevalence and incidence of PD as compared with Caucasian and a few Oriental populations. The mortality rates were comparable. The decreased age-specific PR among slum populations and higher relative risk of death need further probing.

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Figure 1 Sample stratification
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References

    1. Saha SP, Bhattacharya S, Das SK, Maity B, Roy T, Raut DK. Epidemiological study of neurological disorders in a rural population of Eastern India. J Indian Med Assoc 2003;101:299–300, 302–304. - PubMed
    1. Gourie-Devi M, Gururaj G, Satishchandra P, Subbakrishna DK. Prevalence of neurological disorders in Bangalore, India: a community-based study with a comparison between urban and rural areas. Neuroepidemiology 2004;23:261–268. - PubMed
    1. Das SK, Biswas A, Roy T, et al. A random sample survey for prevalence of major neurological disorders in Kolkata. Indian J Med Res 2006;124:163–172. - PubMed
    1. de Rijk MC, Breteler MM, Graveland GA, et al. Prevalence of Parkinson's disease in the elderly: the Rotterdam Study. Neurology 1995;45:2143–2146. - PubMed
    1. Morgante L, Rocca WA, Di Rosa AE, et al; for The Sicilian Neuro-Epidemiologic Study (SNES) Group. Prevalence of Parkinson's disease and other types of parkinsonism: a door-to-door survey in three Sicilian municipalities. Neurology 1992;42:1901–1907. - PubMed

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