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Review
. 2010 Nov;31(Suppl 2):S215-8.
doi: 10.1007/s10072-010-0437-8.

Cognitive impairment in pediatric multiple sclerosis

A Ghezzi  1 , B Goretti, E Portaccio, M Roscio, M P Amato
Affiliations
Review

Cognitive impairment in pediatric multiple sclerosis

A Ghezzi et al. Neurol Sci. 2010 Nov.

Abstract

Cognitive impairment has been recently recognized in patients with pediatric multiple sclerosis in more than 30% of cases. Altered functions with variable frequency are: attention, language (receptive, verbal fluency, naming), visual-spatial and motor functions, spatial memory, executive functions and abstract reasoning. Fatigue and affective disorders are associated, but not correlated with cognitive impairment. The frequency and severity of cognitive impairment increase with time. Cognitive impairment has a negative impact on patient's life limiting social, academic and recreational activities.

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