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Comment
. 2010 Oct;28(10):1026-8.
doi: 10.1038/nbt1010-1026.

Taking the measure of the methylome

Stephan Beck  1
Affiliations
Comment

Taking the measure of the methylome

Stephan Beck. Nat Biotechnol. 2010 Oct.

Abstract

Two comparative studies from the International Human Epigenome Project find high concordance between different methods for measuring genomic methylation.

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Comment on

  • Quantitative comparison of genome-wide DNA methylation mapping technologies.
    Bock C, Tomazou EM, Brinkman AB, Müller F, Simmer F, Gu H, Jäger N, Gnirke A, Stunnenberg HG, Meissner A. Bock C, et al. Nat Biotechnol. 2010 Oct;28(10):1106-14. doi: 10.1038/nbt.1681. Epub 2010 Sep 19. Nat Biotechnol. 2010. PMID: 20852634 Free PMC article.
  • Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.
    Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, Echipare L, O'Geen H, Lister R, Pelizzola M, Xi Y, Epstein CB, Bernstein BE, Hawkins RD, Ren B, Chung WY, Gu H, Bock C, Gnirke A, Zhang MQ, Haussler D, Ecker JR, Li W, Farnham PJ, Waterland RA, Meissner A, Marra MA, Hirst M, Milosavljevic A, Costello JF. Harris RA, et al. Nat Biotechnol. 2010 Oct;28(10):1097-105. doi: 10.1038/nbt.1682. Epub 2010 Sep 19. Nat Biotechnol. 2010. PMID: 20852635 Free PMC article.

References

    1. Epigenomics. 2010 Aug;2(4):587-98 - PubMed
    1. Cancer Res. 2005 Dec 15;65(24):11241-6 - PubMed
    1. Nat Biotechnol. 2010 Oct;28(10):1039-44 - PubMed
    1. Nat Biotechnol. 2010 Oct;28(10):1097-105 - PubMed
    1. Nature. 2009 Nov 19;462(7271):315-22 - PubMed

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