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doi: 10.1016/j.cell.2010.09.046.
The Myc connection: ES cells and cancer
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- PMID: 20946977
- DOI: 10.1016/j.cell.2010.09.046
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The Myc connection: ES cells and cancer
Cell.
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Abstract
Gene profiling experiments have revealed similarities between cancer and embryonic stem (ES) cells. Kim et al. (2010) dissect the gene expression signature of ES cells into three functional modules and find that the Myc module, including genes targeted by Myc-interacting proteins, accounts for most of the similarity between ES and cancer cells.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.Cell. 2010 Oct 15;143(2):313-24. doi: 10.1016/j.cell.2010.09.010. Cell. 2010. PMID: 20946988 Free PMC article.
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