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. 2010 Oct 15;143(2):184-6.
doi: 10.1016/j.cell.2010.09.046.

The Myc connection: ES cells and cancer

Michael E Rothenberg  1 , Michael F Clarke, Maximilian Diehn
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The Myc connection: ES cells and cancer

Michael E Rothenberg et al. Cell. .
Free article

Abstract

Gene profiling experiments have revealed similarities between cancer and embryonic stem (ES) cells. Kim et al. (2010) dissect the gene expression signature of ES cells into three functional modules and find that the Myc module, including genes targeted by Myc-interacting proteins, accounts for most of the similarity between ES and cancer cells.

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